Selank and Semax are registered drugs in Russia, taken as nose drops in short courses. Elsewhere they’re sold as research powder. DSIP’s sleep data are weak, and Cerebrolysin is a hospital drug.
The Russian labels use short courses: Selank (0.15%) for 14 days and Semax (0.1%) for 10–14 days, both as drops in the nose.
DSIP’s insomnia trials found weak effects. In July 2026 FDA’s advisory committee voted 7–6 against allowing it in compounding.
Adamax and Pinealon have no human trials. Their doses are borrowed from Semax and from Russian bioregulator practice.
| Compound | Evidence | Common dose | Frequency | Cycle, first 26 weeks |
|---|---|---|---|---|
| SelankAnxiolytic peptide (tuftsin analog) | Approved drug | ~300 mcg, 1–3× daily | 1–3× daily | 2 weeks on, 2 off |
| SemaxNootropic peptide (ACTH fragment analog) | Approved drug | 200–300 mcg, 2–4× daily | 2–4× daily | 2 weeks on, 1 off |
| Selank + SemaxNootropic blend | Blend | 300 mcg of each, 1–2× daily | 1–2× daily | 2 weeks on, 2 off |
| AdamaxExperimental Semax-derived peptide | Preclinical | ~300 mcg daily | Once daily | No set cycle |
| PinealonShort bioregulator peptide | Preclinical | ~1 mg daily for 10–20 days | Once daily during a course | 2-week course, about every 6 months |
| DSIPSleep and stress neuropeptide | Approved drug | 100–300 mcg before bed | Once nightly | 2 weeks on, 2 off |
| CerebrolysinNeurotrophic peptide preparation | Approved drug | No protocol for research vials | Once daily during a course | 4-week course, about every 4 months |
| DihexaAngiotensin IV analog (HGF/c-Met modulator) | Human studies | 5–20 mg by mouth, once daily | Once daily | No set cycle |
| PE-22-28TREK-1 potassium-channel blocker (spadin analog) | Preclinical | 50–600 mcg daily (no tested dose) | Once daily | No set cycle |
Each draw is worked out for the vial and water shown. The calculator can plan a whole run, including how many vials it takes.
| Period | Dose | Volume |
|---|---|---|
| Days 1–1442 doses | 300 mcg | 0.09 mL |
Mixed as 10 mg + 3 mL (3.333 mg/mL). One vial holds 33 doses, about 11 days at this pace. At this dilution, 0.1 mL holds 333 mcg; most nasal pumps spray 0.05–0.14 mL.
Registered as 0.15% drops: 2 drops per nostril, 3 times a day. From research powder, the volume per dose depends on your dilution.
| Period | Dose | Volume |
|---|---|---|
| Days 1–1456 doses | 300 mcg | 0.09 mL |
Mixed as 10 mg + 3 mL (3.333 mg/mL). One vial holds 33 doses, about 8 days at this pace. At this dilution, 0.1 mL holds 333 mcg; most nasal pumps spray 0.05–0.14 mL.
Registered as 0.1% drops: 2–3 drops per nostril (200–300 mcg), up to 4 times a day for memory and attention problems.
| Period | Dose | Draw |
|---|---|---|
| Nights 1–77 doses | 250 mcg | 10 units |
Mixed as 5 mg + 2 mL (2.5 mg/mL). One vial holds 20 doses, about 2.9 weeks at this pace.
Under the skin, 1–3 hours before bed. The registered form is nasal (300 mcg); injection has no human data.
Semax can be stimulating and disturb sleep, so guides dose it in the morning or early afternoon. Selank is the calmer of the two.
CommunityThe Russian labels say to clear a runny or blocked nose before the drops.
LabelThe registered products are used for 10–14 days at a time, then stopped.
LabelNasal pumps deliver roughly 0.05 to 0.14 mL per spray. Check your pump’s volume before turning a dose into sprays.
Purity and content can differ from the Russian products, whose doses come from their own labels.
Doses tagged Community come from public dosing guides and user reports, checked against at least two of them. Those sites aren’t named here because many of them sell peptides or earn commissions on them.
Each compound’s page lists its own sources.
The approved GLP-1 drugs, the newer investigational ones, and fat-loss peptides with far less evidence.
BPC-157, TB-500, thymosin beta-4 and their blends, plus peptides aimed at joints, wounds, the gut and nerves.
GHRH analogs, ghrelin-receptor agonists such as ipamorelin and MK-677, IGF-1 analogs and follistatin.
Copper peptides, cosmetic peptides and the two melanotans.
NAD+, MOTS-c, SS-31, glutathione, humanin, FOXO4-DRI and the bioregulator courses.
PT-141, hCG, kisspeptin-10, oxytocin, gonadorelin and triptorelin.
Thymosin alpha-1, Thymalin, KPV, VIP, LL-37 and larazotide.