Vial Guide

PT-141 10 mg vial

How much bacteriostatic water to add to a 10 mg vial of PT-141, the syringe units for each common dose, and how many doses the vial holds.

Water
2 mL
Strength
5 mg/mL
Common dose
1.75 mg
Draw
35 units0.35 mL
Doses per vial
5

The short answer

Mixed with 2 mL of bacteriostatic water, a 10 mg vial of PT-141 holds 5 mg/mL. A 1.75 mg dose is then 35 units (0.35 mL) on a U-100 insulin syringe, and the vial holds about 5 doses of that size.

Approved drug. FDA-approved in 2019 as Vyleesi for acquired, generalized low sexual desire in premenopausal women. Other use is off-label.
PT-141 page

How much water

The water only sets the strength; the dose and the number of doses in the vial stay the same. Draws are on a U-100 insulin syringe, where 1 unit is 0.01 mL.

Water addedStrengthPer syringe unitDraw for 1.75 mg
1 mL10 mg/mL100 mcg17.5 units (0.17 mL)
2 mL5 mg/mL50 mcg35 units (0.35 mL)
3 mL3.333 mg/mL33.3 mcg52.5 units (0.53 mL)

Dose chart

Syringe units for each common dose at each water volume. Select a cell to open it in the calculator.

DoseWater added
1 mL2 mL3 mL
1 mg
1.5 mg
1.75 mg

Draws over 100 units show in mL. Faded values are under 2 units, which is hard to measure. Check that your vial holds the larger volumes.

Where the doses come from

  • Label 1.75 mg at least 45 minutes before sexual activity. No more than 1 dose in 24 hours or 8 doses a month.
  • Community Off-label users often start at 1 mg to gauge nausea.

Doses are what labels, trials or community reports reference, not recommendations. PT-141’s page has the cycle, side effects, cautions and sources.

Mixing and storage

  1. PrepareLet a refrigerated vial come to room temperature, and wipe both stoppers with an alcohol swab.
  2. Add 2 mLDraw 2 mL of bacteriostatic water and let it run slowly down the inside wall of the vial.
  3. Swirl, don’t shakeSwirl gently until the powder dissolves and the liquid is clear.
  4. Label itWrite the date and the strength, 5 mg/mL, on the vial.

Storage: Mixed: 2–8 °C, protected from light.

The reconstitution guide covers each step, and the units page explains syringe markings.

Questions

How much water do I add to a 10 mg vial of PT-141?

There’s no single right amount: the water only sets the strength. With 2 mL of bacteriostatic water, a 10 mg vial holds 5 mg/mL. With 1 mL it’s 10 mg/mL; with 3 mL it’s 3.333 mg/mL. Less liquid makes each dose a smaller draw; more makes small doses easier to measure.

How many units is 1.75 mg of PT-141?

With 2 mL in a 10 mg vial, 1.75 mg is 35 units (0.35 mL) on a U-100 insulin syringe. With 1 mL, 17.5 units (0.17 mL); with 3 mL, 52.5 units (0.53 mL).

How many doses are in a 10 mg vial of PT-141?

About 5 doses of 1.75 mg, or 10 of 1 mg or 6 of 1.5 mg.

How long does a mixed vial of PT-141 keep?

Mixed: 2–8 °C, protected from light.

Sources

  • Vyleesi (bremelanotide) label (DailyMed)

The math on this page uses the doses and storage on PT-141’s page.