Cortagen 20 mg vial
How much bacteriostatic water to add to a 20 mg vial of Cortagen, the syringe units for each common dose, and how many doses the vial holds.
- Water
- 2 mL
- Strength
- 10 mg/mL
- Common dose
- 1 mg
- Draw
- 10 units0.10 mL
- Doses per vial
- 20
The short answer
Mixed with 2 mL of bacteriostatic water, a 20 mg vial of Cortagen holds 10 mg/mL. A 1 mg dose is then 10 units (0.10 mL) on a U-100 insulin syringe, and the vial holds about 20 doses of that size. Taken 1× per day, it lasts about 2.9 weeks.
How much water
The water only sets the strength; the dose and the number of doses in the vial stay the same. Draws are on a U-100 insulin syringe, where 1 unit is 0.01 mL.
| Water added | Strength | Per syringe unit | Draw for 1 mg |
|---|---|---|---|
| 1 mL | 20 mg/mL | 200 mcg | 5 units (0.05 mL) |
| 2 mL | 10 mg/mL | 100 mcg | 10 units (0.10 mL) |
| 3 mL | 6.667 mg/mL | 66.7 mcg | 15 units (0.15 mL) |
Dose chart
Syringe units for each common dose at each water volume. Select a cell to open it in the calculator.
| Dose | Water added | ||
|---|---|---|---|
| 1 mL | 2 mL | 3 mL | |
| 0.2 mg | |||
| 0.3 mg | |||
| 0.4 mg | |||
| 0.6 mg | |||
| 0.75 mg | |||
| 1 mg | |||
| 1.5 mg | |||
| 2 mg | |||
Draws over 100 units show in mL. Faded values are under 2 units, which is hard to measure. Check that your vial holds the larger volumes.
Where the doses come from
- Community Guides overlap at about 1 mg injected once daily for 10–20 days; the range runs from 100 mcg to 10 mg. No human dose-finding data exist.
Doses are what labels, trials or community reports reference, not recommendations. Cortagen’s page has the cycle, side effects, cautions and sources.
Mixing and storage
- PrepareLet a refrigerated vial come to room temperature, and wipe both stoppers with an alcohol swab.
- Add 2 mLDraw 2 mL of bacteriostatic water and let it run slowly down the inside wall of the vial.
- Swirl, don’t shakeSwirl gently until the powder dissolves and the liquid is clear.
- Label itWrite the date and the strength, 10 mg/mL, on the vial.
Storage: Powder: −20 °C. Mixed: 2–8 °C, use within about 4 weeks.
The reconstitution guide covers each step, and the units page explains syringe markings.
Questions
How much water do I add to a 20 mg vial of Cortagen?
There’s no single right amount: the water only sets the strength. With 2 mL of bacteriostatic water, a 20 mg vial holds 10 mg/mL. With 1 mL it’s 20 mg/mL; with 3 mL it’s 6.667 mg/mL. Less liquid makes each dose a smaller draw; more makes small doses easier to measure.
How many units is 1 mg of Cortagen?
With 2 mL in a 20 mg vial, 1 mg is 10 units (0.10 mL) on a U-100 insulin syringe. With 1 mL, 5 units (0.05 mL); with 3 mL, 15 units (0.15 mL).
How many doses are in a 20 mg vial of Cortagen?
About 20 doses of 1 mg, or 13 of 1.5 mg or 10 of 2 mg. Taken 1× per day at 1 mg, it lasts about 2.9 weeks.
How long does a mixed vial of Cortagen keep?
Powder: −20 °C. Mixed: 2–8 °C, use within about 4 weeks.
Sources
- Anisimov et al., brain cortex tetrapeptide Cortagen, its origin from Cortexin and gene expression in mouse heart (Neuro Endocrinol Lett 2004) PMID 15159690
- Turchaninova et al., Cortagen and sciatic nerve regeneration in rats (Bull Exp Biol Med 2000) PMID 11276314
- Zarubina and Shabanov, Cortexin and Cortagen in rats with chronic brain ischemia (Eksp Klin Farmakol 2011, in Russian) PMID 21476278
- Khavinson, tissue-specific effects of Cortagen, Epithalon, Livagen and Vilon in rat tissue cultures (Bull Exp Biol Med 2001) PMID 11713572
The math on this page uses the doses and storage on Cortagen’s page.