Vial Guide

Bronchogen 20 mg vial

How much bacteriostatic water to add to a 20 mg vial of Bronchogen, the syringe units for each common dose, and how many doses the vial holds.

Water
2 mL
Strength
10 mg/mL
Common dose
1 mg
Draw
10 units0.10 mL
Doses per vial
20

The short answer

Mixed with 2 mL of bacteriostatic water, a 20 mg vial of Bronchogen holds 10 mg/mL. A 1 mg dose is then 10 units (0.10 mL) on a U-100 insulin syringe, and the vial holds about 20 doses of that size. Taken 1× per day, it lasts about 2.9 weeks.

Preclinical. Two rat studies of COPD-like lung damage from a St. Petersburg pulmonology group, plus cell and DNA-binding work from Vladimir Khavinson’s group and its partners. No human study has been published. Russia registers it only as a dietary supplement, not a medicine.
Bronchogen page

How much water

The water only sets the strength; the dose and the number of doses in the vial stay the same. Draws are on a U-100 insulin syringe, where 1 unit is 0.01 mL.

Water addedStrengthPer syringe unitDraw for 1 mg
1 mL20 mg/mL200 mcg5 units (0.05 mL)
2 mL10 mg/mL100 mcg10 units (0.10 mL)
3 mL6.667 mg/mL66.7 mcg15 units (0.15 mL)

Dose chart

Syringe units for each common dose at each water volume. Select a cell to open it in the calculator.

DoseWater added
1 mL2 mL3 mL
0.1 mg
0.2 mg
0.3 mg
0.5 mg
0.6 mg
1 mg
2 mg

Draws over 100 units show in mL. Faded values are under 2 units, which is hard to measure. Check that your vial holds the larger volumes.

Where the doses come from

  • Community Injected: 1–2 mg once daily for 10–20 days in most guides; one uses 100–500 mcg a day. No human dosing study exists.
  • Community By mouth: the Russian supplement’s directions are 1–2 capsules (100 mcg of peptide each) 1–2× daily with meals for 1 month, repeated after 4–6 months. A supplement label, not a drug approval.

Doses are what labels, trials or community reports reference, not recommendations. Bronchogen’s page has the cycle, side effects, cautions and sources.

Mixing and storage

  1. PrepareLet a refrigerated vial come to room temperature, and wipe both stoppers with an alcohol swab.
  2. Add 2 mLDraw 2 mL of bacteriostatic water and let it run slowly down the inside wall of the vial.
  3. Swirl, don’t shakeSwirl gently until the powder dissolves and the liquid is clear.
  4. Label itWrite the date and the strength, 10 mg/mL, on the vial.

Storage: Powder: −20 °C. Mixed: 2–8 °C, use within about 4 weeks. Russian capsules: 2–25 °C, dry and away from light.

The reconstitution guide covers each step, and the units page explains syringe markings.

Questions

How much water do I add to a 20 mg vial of Bronchogen?

There’s no single right amount: the water only sets the strength. With 2 mL of bacteriostatic water, a 20 mg vial holds 10 mg/mL. With 1 mL it’s 20 mg/mL; with 3 mL it’s 6.667 mg/mL. Less liquid makes each dose a smaller draw; more makes small doses easier to measure.

How many units is 1 mg of Bronchogen?

With 2 mL in a 20 mg vial, 1 mg is 10 units (0.10 mL) on a U-100 insulin syringe. With 1 mL, 5 units (0.05 mL); with 3 mL, 15 units (0.15 mL).

How many doses are in a 20 mg vial of Bronchogen?

About 20 doses of 1 mg, or 33 of 0.6 mg or 10 of 2 mg. Taken 1× per day at 1 mg, it lasts about 2.9 weeks.

How long does a mixed vial of Bronchogen keep?

Powder: −20 °C. Mixed: 2–8 °C, use within about 4 weeks. Russian capsules: 2–25 °C, dry and away from light.

Other vial sizes

Sources

  • Kuzubova et al., Bronchogen and the bronchial lining in rats with obstructive lung disease (Bull Exp Biol Med 2015) PMID 26468022
  • Titova et al., anti-inflammatory and regenerative effect of Bronchogen in a rat model of obstructive lung disease (Ross Fiziol Zh 2017, in Russian) PMID 30199201
  • Khavinson et al., peptide regulation of gene expression and protein synthesis in bronchial epithelium (Lung 2014) PMID 25015171
  • Khavinson et al., tissue-specific peptides, including bronchogen (Ala-Glu-Asp-Leu), and cell differentiation (Bull Exp Biol Med 2012) PMID 22808515
  • Bronchogen dietary supplement directions: composition, dosing, contraindications and storage (RLS Russia entry; instructions approved October 17, 2012)

The math on this page uses the doses and storage on Bronchogen’s page.

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